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J Neurol Neurosurg Psychiatry 75:1396-1400 doi:10.1136/jnnp.2003.030007
  • Paper

Right prosubiculum amyloid plaque density correlates with anosognosia in Alzheimer’s disease

Table 2

 Senile plaque and neurofibrillary tangle counts in four brain regions

+Aware (n = 23) −Aware (n = 18) +Aware (n = 13)* −Aware (n = 13)*
Values are means (SD).
*Subset matched for dementia severity.
†p = 0.015; ‡p = 0.002; §p = 0.051.
EC, entorhinal cortex; L, left; NFT, neurofibrillary tangle; PRO, prosubiculum of the hippocampus; R, right; SMF, superior and middle frontal gyri; ST, superior temporal isocortex; SP, senile plaque; +Aware, without anosognosia; −Aware, with anosognosia.
SMF R SP 23 (19) 21 (13) 20 (11) 22 (14)
R NFT 6 (7) 8 (7) 7 (6) 7 (6)
L SP 22 (17) 20 (12) 19 (11) 22 (13)
L NFT 7 (7) 9 (8) 9 (7) 9 (9)
ST R SP 20 (17) 17 (12) 18 (8) 15 (9)
R NFT 9 (10) 11 (10) 10 (9) 10 (10)
L SP 22 (21) 23 (22) 20 (16) 25 (25)
L NFT 9 (9) 12 (10) 10 (9) 11 (10)
PRO R SP 7 (4)† 11 (6)† 6 (4)‡ 12 (4)‡
R NFT 19 (16) 24 (15) 22 (19) 28 (14)
L SP 9 (4) 12 (6) 8 (4)§ 12 (6)§
L NFT 23 (17) 28 (16) 25 (20) 33 (15)
EC R SP 16 (9) 17 (10) 16 (11) 16 (11)
R NFT 15 (8) 16 (9) 15 (8) 15 (9)
L SP 15 (11) 15 (10) 16 (14) 12 (7)
L NFT 15 (8) 16 (8) 15 (8) 16 (7)

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