rss
J Neurol Neurosurg Psychiatry 75:1467-1469 doi:10.1136/jnnp.2003.031237
  • Short report

Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson’s disease is related to cognitive impairment

Table 1

 The clinical characteristics and the atrophy values for patients with Parkinson’s disease and controls

N Sex (F/M) Age (years)* UPDRS* Duration (years)† MMSE‡ PFC right‡ PFC left‡ Hippocampus right‡ Hippocampus left‡
*Values are mean and SD; †values are mean, SD, and range; ‡values are mean, SD, median, and range.
F, female; M, male; MMSE, Mini-Mental State Examination; PFC, prefrontal cortex; UPDRS, Unified Parkinson’s Disease Rating Scale.
Patients 20 7/13 61.3; 7.0 29.7 (6.3) 1.7; 0.8; 26.7; 1.5; 1.90; 0.64; 1.90; 0.64; 1.15; 0.81; 1.05; 0.89;
0.7–4 26.5; 24–29 2; 0–3 2; 0–3 1; 0–2 1; 0–3
Controls 22 13/9 65.7; 9.3 28.8; 1.1; 1.73; 0.88; 1.73; 0.88; 0.45; 0.67; 0.64; 0.66;
29; 27–30 2; 0–4 2; 0–4 0; 0–2 1; 0–2
p Value 0.12 0.09 <0.0001 0.02 0.02 0.001 0.01

This Article

Latest from Practical Neurology

Latest from Practical Neurology

Free sample
This recent issue is free to all users to allow everyone the opportunity to see the full scope and typical content of JNNP.
View free sample issue >>

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

  • BMJ Careers - Latest Neurology and Neurosurgery jobs

    Latest neurology and neurosurgery jobs