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J Neurol Neurosurg Psychiatry 75:1737-1741 doi:10.1136/jnnp.2004.038471
  • Paper

The effects of water ingestion on orthostatic hypotension in two groups of chronic autonomic failure: multiple system atrophy and pure autonomic failure

Table 4

 Dynamap blood pressure and heart rate in patients with PAF and MSA on standing, before and after ingestion of 480 ml water

PAF (n = 7) MSA (n = 7)
Stand 0 (before water) Stand 1 (15 min after water) Stand 2 (35 min after water) Stand 0 (before water) Stand 1 (15 min after water) Stand 2 (35 min after water)
Values in mmHg (SD) and beats/min (SD): Stand 1 and 2 compared with Stand 0.
* = p<0.05; ** = p<0.01; *** = p<0.001.
Seated value just prior to stand
    SBP 103.9 (30.1) 126.4 (32.9) 137.9 (30.5) 117.3 (18.6) 119.4 (26.7) 129.9 (21.0)
    DBP 66.3 (11.9) 78.7 (10.8) 81.1 (14.2) 73.0 (13.8) 74.1 (17.0) 79.7 (15.1)
    HR 71.1 (11.4) 66.0 (5.2) 65.3 (6.8) 76.7 (11.1) 75.7 (9.3) 75.0 (10.4)
3 min of stand
    SBP 68.4 (18.5)** 97.3 (25.4)* 96.9 (26.2)* 90.6 (19.5)** 106.0 (22.2)** 102.3 (23.6)*
    DBP 43.4 (10.7)** 61.0 (16.3)* 63.3 (16.0)** 59.6 (14.8)** 66.3 (10.4) 64.7 (13.0)
    HR 77.0 (13.9) 69.7 (8.2)* 69.9 (8.1)* 89.8 (14.6) 82.8 (14.8)* 85.8 (14.7)
5 min of stand
    SBP 64.4 (20.8)** 88.9 (22.5)* 92.1 (25.1)** 90.3 (24.5)** 101.7 (23.3)* 98.6 (21.9)**
    DBP 40.4 (12.1)** 59.4 (16.5)* 57.7 (17.2)* 58.9 (15.2)** 67.3 (15.9**) 63.0 (15.9)*
    HR 75.1 (13.1) 69.1 (8.9) 70.7 (8.8) 89.8 (16.8) 85.3 (15.7)* 88.5 (13.5)

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