Table 2
Synopsis of the results of the voxel based morphometry group analysis
| Anatomical region | Talairach coordinates | z Score | ||
|---|---|---|---|---|
| x | y | z (mm) | ||
| Anatomical regions, Talairach coordinates of the centres of voxel clusters, and z scores of all cerebral regions showing significant differences between the Huntington’s disease and control groups (thresholded at p<0.001 and corrected for multiple comparisons). | ||||
| Striatum | ||||
| L caudate nucleus (head) | 12 | −1 | 17 | 15.98 |
| L caudate nucleus (head) | 8 | 15 | 3 | 14.61 |
| R caudate nucleus (head) | −11 | 9 | 13 | 10.56 |
| R caudate nucleus (head) | −7 | 19 | 3 | 16.14 |
| L caudate nucleus (body) | 5 | 11 | 4 | 8.85 |
| R caudate nucleus (body) | −5 | 5 | 7 | 8.61 |
| L caudate nucleus (tail) | 20 | −28 | 17 | 7.01 |
| R caudate nucleus (tail) | −20 | −32 | 17 | 8.11 |
| L putamen (ventral) | 22 | 15 | 6 | 9.13 |
| L putamen (dorsal) | 23 | 0 | 12 | 10.89 |
| R putamen (ventral) | −22 | 16 | 4 | 10.42 |
| R putamen (dorsal) | −23 | −3 | 13 | 11.08 |
| Extrastriatal areas | ||||
| R precentral gyrus | −29 | −23 | 60 | 8.09 |
| R paracentral lobule | −1 | −36 | 49 | 12.69 |
| L operculum | 43 | −12 | 11 | 7.97 |
| R operculum | −35 | −26 | 13 | 8.84 |
| Hypothalamus | 1 | 4 | −10 | 10.74 |
