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J Neurol Neurosurg Psychiatry 2004;75:368-369 doi:10.1136/jnnp.2003.021691
  • Lesson of the month

Idiopathic recurrent stupor: a warning

  1. R Granot1,
  2. S F Berkovic2,
  3. S Patterson2,
  4. M Hopwood3,
  5. R Mackenzie1
  1. 1Institute of Neurological Sciences, Prince of Wales Hospital, Randwick, NSW, Australia
  2. 2Epilepsy Research Institute, Department of Medicine (Neurology), University of Melbourne, Heidelberg, Victoria, Australia
  3. 3Department of Psychiatry, University of Melbourne
  1. Correspondence to:
 Dr Roderick Mackenzie
 PO Box 2043, Taren Point, NSW 2229, Australia; macraoptushome.com.au
  • Received 25 June 2003
  • Accepted 9 July 2003

Abstract

A proposal that an endogenous benzodiazepine-like agent named endozepine-4 might be responsible for presentations of recurrent stupor has gained wide acceptance. A case of recurrent stupor over two decades is presented with many similarities to previous cases of “endozepine stupor”. This case, however, was caused by exogenous benzodiazepine administration and serves as a warning to clinicians to beware of this diagnosis.

Footnotes

  • Competing interests: none declared

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