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J Neurol Neurosurg Psychiatry 75:669-676 doi:10.1136/jnnp.2003.028175
  • Neuroscience for neurologists

Applications of positron emission tomography (PET) in neurology

Table 2

Summary of positron emission tomography (PET) findings in parkinsonian syndromes

PET tracer Parkinson’s disease Progressive supranuclear palsy Multiple system atrophy Corticobasal degeneration
18F-Dopa Asymmetric reduction (putamen > caudate) Symmetrical reduction (caudate  =  putamen) Symmetrical reduction (caudate  =  putamen) Asymmetric reduction (caudate  =  putamen)
18FDG Normal/raised in striatum. Reduced in temporoparietal cortex Reduced in bilateral striatum and frontal cortices Reduced in striatum, brainstem, and cerebellum Asymmetric reduction in striatum, thalamus, frontal and temporoparietal cortices

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