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J Neurol Neurosurg Psychiatry 75:1270-1274 doi:10.1136/jnnp.2003.030189
  • Paper

Alzheimer’s disease—one clinical syndrome, two radiological expressions: a study on blood pressure

Table 2

 Mean systolic and diastolic blood pressure, prevalence of hypertension, and pulse pressure by absence or presence of small vessel disease in patients with Alzheimer’s disease*

Age at MRI Small vessel disease
Absent (n = 36) Present (n = 116)
*Values are age and sex adjusted means (SD) or percentages. Differences between those with or without small vessel disease were tested by age and sex adjusted analysis of covariance.
†p = 0.02; ‡p = 0.03; ¶p = 0.01.
MRI, magnetic resonance imaging.
Systolic blood pressure <65 years (n = 50) 135.7 (20.5) 149.9 (19.3)†
⩾65 years (n = 102) 156.5 (21.0) 151.9 (23.1)
Overall (n = 152) 146.9 (22.2) 150.9 (22.1)
Diastolic blood pressure <65 years 84.0 (11.6) 88.0 (12.1)
⩾65 years 86.3 (8.8) 86.2 (11.1)
Overall 85.2 (10.2) 86.7 (11.4)
Hypertension <65 years 45.1 75.6‡
⩾65 years 92.6 80.3
Overall 71.6 77.8
Pulse pressure <65 years 51.7 (11.5) 61.9 (14.4)¶
⩾65 years 70.1 (16.4) 65.7 (18.7)
Overall 61.7 (16.1) 64.3 (17.7)

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