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J Neurol Neurosurg Psychiatry 2005;76:1331 doi:10.1136/jnnp.2005.072017
  • HIV and stroke
  • Editorial commentary

HIV infection and stroke: if not protein S deficiency then what explains the relationship?

  1. A I Qureshi
  1. Correspondence to:
 Dr Adnan I Qureshi
 Zeenat Qureshi Stroke Research Center, 90 Bergen Street, DOC – 8100, Newark, NJ 07103, USA; aiqureshihotmail.com

    The use of anti-retroviral agents in HIV infection is associated with an increased risk of cardiovascular disease

    Over the last two decades, reports have suggested that cardiovascular diseases such as angina, myocardial infarction, and stroke can be observed in young patients with human immunodeficiency virus (HIV) infection.1 As we review this issue, three questions need to be addressed: (1) is the risk of stroke higher in HIV infected patients?; (2) what is the underlying mechanism for the increased risk; and (3) how is the risk modified by the use of new anti-retroviral agents?

    Engstrom et al2 conducted a …

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