Article Text
Short report
Interferon alfa treatment for Sjögren’s syndrome associated neuropathy
Abstract
Treatment response to interferon alfa (IFNα) is described in three consecutive cases of two forms of Sjögren’s syndrome associated neuropathy (SSN)—two with sensory ataxic ganglionopathy and one with sensorimotor neuropathy with demyelinating features. All responded well to IFNα in terms of neuropathic symptoms, sicca symptoms, antibody titres, and findings in salivary gland biopsy specimens. IFNα thus showed promise in treating both SSN and the underlying Sjögren’s syndrome.
- CV, conduction velocity
- IFNα, interferon alfa
- IVIG, intravenous immunoglobulin
- SEP, somatosensory evoked potentials
- SNAP, sensory nerve action potential
- SSA/SSB, Sjögren’s syndrome associated antibody A and B
- SSN, Sjögren’s syndrome associated neuropathy
- Sjögren’s syndrome
- interferon alfa
- neuropathy
Statistics from Altmetric.com
Footnotes
-
Competing interests: none declared