Article Text

PDF

Diseases of the nervous system: patients’ aetiological beliefs
  1. A Croquelois1,2,
  2. G Assal1,
  3. J-M Annoni1,
  4. F Staub1,
  5. A Gronchi1,
  6. L Bruggimann1,
  7. S Dieguez1,
  8. J Bogousslavsky1
  1. 1Neurology Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland
  2. 2Institute of Cellular Biology and Morphology, University of Lausanne, Rue du Bugnon 9, CH-1005 Lausanne, Switzerland
  1. Correspondence to:
 Dr J Bogousslavsky
 Neurology Department, Centre Hospitalier Universitaire Vaudois (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland; julien.bogousslavskychuv.hospvd.ch

Abstract

Background: Patients’ opinions about the aetiology of their disease and the implications for compliance have not been well documented at this time.

Objective: To investigate prospectively aetiological beliefs of a cohort of neurological inpatients.

Methods: Within two days of admission, patients orally answered a short questionnaire regarding their beliefs about the aetiology of their disease and the possible influence of psychological factors, stress, fatigue, excessive work or other activities, poor lifestyle, conflict with another person, a tragic event, chance, and destiny.

Results: Of the 342 patients who participated in the study, 49% spontaneously said that they had no idea of what could have caused their disease, 15% gave a congruent medical explanation, 11% mentioned stress and fatigue as a precipitating factor, and 6% evoked a non-congruent medical explanation. Thirty six per cent thought that psychological factors had triggered their disease; such factors being blamed by a higher proportion of young patients and patients with chronic central nervous system diseases. The triggering factors most often blamed were stress (48%, especially by patients with headache), fatigue (51%), chance (54%), and destiny (43%).

Conclusions: Patients’ aetiological beliefs only partially concur with medical opinion and this may influence compliance with treatment. This statement should be explored and confirmed by further studies—for example, in cerebrovascular risk factor follow up.

  • CL, confidence limit
  • CNS, central nervous system
  • PNS, peripheral nervous system
  • central nervous system diseases
  • aetiology
  • patient compliance
  • adaptation
  • psychological
  • doctor–patient relations

Statistics from Altmetric.com

Patients are often unaware of, or do not understand about, recent developments in molecular and genetic medicine and more technical interventional therapies. Thus when patients search for explanations for triggers and the evolution of their disorder they often blame, for instance, psychological factors or special events.

We hypothesised that this could result in divergence of opinion between the patient and the doctor, which, in turn, might lead to poor compliance with the proposed treatment.1,2 A British study of patients in general practice showed that only half the patients thought they would benefit from medical treatment or hospitalisation for investigations.3 The failure of conventional medicine to take into account psychological aspects of illness may be one reason for the recent enthusiasm for alternative and complementary therapies.4–6 Another reason for evaluating patients’ beliefs about psychological factors is that these factors have been described as a possible influence on the triggering of diseases.7 In addition, there is recent evidence for a beneficial effect of spiritual belief on the evolution of chronic disorders and on patients’ ability to cope with the disease.8,9 Stress and excessive workload have also been recently recognised as possible factors in the development of chronic pain syndrome, with or without anatomical lesions.10,11

To evaluate these aspects of clinical practice, we asked patients to reply orally to a short questionnaire during the first two days after admission to a neurology inpatient department.

PATIENTS AND METHODS

Of 750 consecutive inpatients admitted to our neurology department between November 2001 and June 2002, 41 patients refused to answer the short questionnaire and 367 were unable to answer within two days of admission (critically ill, demented, confused, severely aphasic, and anosognosic patients). The remaining 342 patients (49% women, 51% men; mean (SD) age 61 (19) years) participated in the study. These patients answered a short questionnaire consisting of three questions:

  1. The first question was open ended to evaluate spontaneous answers: “What do you think triggered your disease?”

  2. The second question assessed psychological factors in general: “Do you think that psychological factors played a role in triggering it?”

  3. The third question explored whether the following factors could have triggered the patient’s disease: stress, fatigue, excessive work or other activities, poor lifestyle, conflict with another person, tragic event, chance, and destiny.

The diagnosis was made on the basis of a standard, generally accepted work up and patients were classified as having stroke (n = 177), chronic central nervous system (CNS) disease (n = 41; mainly parkinsonism and inflammatory diseases), epilepsy (n = 27), headaches (n = 16), peripheral nervous system (PNS) disease (n = 30), or non-classified diseases (n = 51).

RESULTS

When answering the first open ended question, 49% of patients included in the study spontaneously admitted that they had no idea of what could have caused their disease (95% confidence limit (CL) 43.7% to 54.3%), 15% gave a congruent medical explanation (95% CL 11.2% to 18.8%), 11% mentioned stress and fatigue as a precipitating factor (95% CL 7.7% to 14.3%), 6% mentioned a psychological event or a dysthymia (95% CL 3.5% to 8.5%), and 6% gave a non-congruent medical explanation (95% CL 3.5% to 8.5%). Some answers could not be classified into any of the aforementioned categories: one patient said that he was convinced that a portable phone antenna placed next to his house was responsible for triggering his transient aphasia symptoms, and another patient, who had had a right middle cerebral artery stroke, blamed the shock of France’s election in 2002 when the far right candidate qualified for a second run.

When asked if psychological factors were responsible for triggering their disease, 36% of patients gave an affirmative answer (95% CL 30.9% to 41.1%). Internal factors, such as stress (48%, 95% CL 42.7% to 53.3%) and fatigue (51%, 95% CL 45.7% to 56.3%), and those factors which cannot be influenced, such as chance (54%, 95% CL 48.7% to 59.3%) and destiny (43%, 95% CL 37.8% to 48.2%), were blamed more often than external factors, such as excess work or other activities (30%, 95% CL 25.1% to 34.9%), poor lifestyle (16%, 95% CL 12.1% to 19.9%), conflict with another person (14%, 95% CL 10.3% to 17.7%), or a tragic event (18%, 95% CL 13.9% to 22.1%). Significantly different proportions of patients from the different diagnostic groups considered psychological factors as a triggering factor (fig 1A; χ2 test, p = 0.026), mainly due to the small proportion of patients with PNS diseases and stroke who blamed these factors. In the group of patients with stroke (fig 1B–D), no significant differences were found between the sexes (81 women, 96 men) (χ2 test, p = 0.21), among different stroke locations (χ2 test, p = 0.43), and between the two age groups, despite a strong tendency for younger patients (<65 years, n = 54) to evoke these factors more frequently than older patients (>65 years, n = 123) (χ2 test, p = 0.06). The age distribution was not significantly different among the subgroups based on stroke location (right internal carotid artery (ICA, n = 48), 67 (18) years; left ICA, n = 54, 71 (13) years; vertebrobasilar, n = 75, 69 (13), ANOVA, p = 0.76) and between the sexes (women, 71 (15) years; men, 67 (15) years, Student’s t test, p = 0.08).

Figure 1

 Percentage of affirmative answers for psychological factors. (A) Comparison between different diagnostic groups. (B–D) Comparison of the patients with stroke by (B) age, (C) sex, and (D) location of stroke (for statistics, see text). Left ICA, left internal carotid artery territory; PNS, peripheral nervous system; right ICA, right internal carotid artery territory; VB, vertebrobasilar territory.

The proportion of patients in the different diagnostic groups who considered stress (χ2 test, p = 0.029) as a triggering factor was significantly different, mainly due to the high proportion of patients with chronic primary headache blaming this factor. A significant difference was also found for destiny (χ2 test, p = 0.043), mainly due to a low frequency of affirmative answers in the PNS diseases group (table 1).

Table 1

 Factors blamed by the different groups (%)

DISCUSSION

As the understanding of disease mechanisms and the diagnostic tools used become more complex and specialised, patients’ may only partially comprehend their disease. Some beliefs of patients may overlap those of their doctors and some may not, and this could influence their compliance with therapy.1,2 In our study, only 15% of patients gave a congruent medical explanation when asked about what could have caused their disease and more than a third believed that psychological factors had played a role in triggering it. Only 16% of stroke patients mentioned a poor lifestyle, whereas many studies have described environmental and lifestyle factors as important in causing cerebrovascular diseases.12,13 In contrast, chance and destiny were frequently mentioned by the patients, which, at least for cerebrovascular disease, does not agree with the medical opinion that genetic, environmental, and lifestyle factors are responsible for the development of the majority of cerebrovascular events.

On the other hand, some studies have described psychological factors in triggering of various diseases such as coronary heart disease,14 fatigue and excessive work as important in the regulation of biological parameters, such as lipid profiles,15 and psychological events as modulators of immune response.16 Other studies have evoked stress and fatigue as worsening factors for headaches and chronic CNS diseases, respectively.17–19

In summary, patients’ beliefs about factors triggering neurological disease only partially concur with medical opinion. If doctors paid particular attention to their beliefs when explaining the medical point of view regarding triggering of their disease, patients’ compliance with treatment could improve. A future development may be to repeat this study with patients with heart (coronary artery) diseases and compare the results with those of the present study. We would expect the results from such a study to be closer to those of our patients with PNS diseases than those of the patients with CNS diseases. Asking patients’ relatives the same questions could also provide new insights into patient care, as relatives often influence compliance with therapy. It should also be confirmed whether patients’ beliefs influence compliance—for example, in cerebrovascular risk factor follow up after stroke.

REFERENCES

View Abstract

Footnotes

  • Competing interests: none declared

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.