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J Neurol Neurosurg Psychiatry 2005;76:622 doi:10.1136/jnnp.2004.055376
  • Guillain–barré syndrome
  • Editorial commentary

Prognosis in the acute motor axonal form of Guillain–Barré syndrome

  1. C M Gabriel
  1. Correspondence to:
 Dr C M Gabriel
 St Mary’s Hospital, Praed Street, London W2 1NY, UK; carolyn.gabrielst-marys.nhs.uk

    Prognosis in axonal Guillain–Barré syndrome

    A primary axonal form of Guillain–Barré syndrome was first described by Feasby and colleagues1 in 1986. Initial indications were that this had a worse prognosis than demyelinating forms of the disease and it was suggested that recovery might require axonal regeneration along the entire length of the nerve fibre. In the intervening years it has become apparent that recovery from acute motor axonal neuropathy (AMAN) may actually be either rapid or slow. This is confirmed in a paper by Hiraga and colleagues (this issue, pp 719–22),2 and in addition they observed that in patients with slow recovery, clinical improvement to independent …

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