Table 1
Clinical profiles of eight patients with pure autonomic failure at their first visit
| Variable | Patient | |||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| *Normal range 150 to 450 pg/ml. | ||||||||
| F, female; M, male; y, years. | ||||||||
| Sex | M | M | M | M | M | M | M | F |
| Onset age (y) | 35 | 68 | 72 | 78 | 50 | 52 | 51 | 50 |
| Time until first evaluation (y) | 17 | 1 | 10 | 5 | 27 | 7 | 5 | 13 |
| Duration of observation (y) | 32 | 7 | 12 | 12 | 32 | 14 | 15 | 29 |
| Hypohidrosis | + | + | + | + | + | + | + | + |
| Faintness | + | + | + | + | + | + | + | + |
| Syncope | – | – | – | – | + | + | + | + |
| Constipation | + | – | – | – | + | – | + | – |
| Difficulty in urination | – | – | + | – | + | – | – | – |
| Incontinence/urinary urgency | – | – | – | – | – | + | + | + |
| Respiratory disturbance | – | – | – | – | – | – | – | – |
| Plasma noradrenaline (pg/ml) * | 30 | 43 | 25 | 83 | 50 | 34 | 14 | 10 |
| Orthostatic hypotension | + | + | + | + | + | + | + | + |
| Denervation supersensitivity | + | + | + | + | + | + | + | + |
| Modified Rankin scale | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
