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J Neurol Neurosurg Psychiatry 2006;77:1238-1243 doi:10.1136/jnnp.2006.089391
  • Paper

Functional status and use of healthcare facilities in long-term survivors of transient ischaemic attack or minor ischaemic stroke

  1. I van Wijk1,
  2. E Lindeman2,
  3. L J Kappelle1,
  4. J van Gijn1,
  5. P J Koudstaal3,
  6. J W Gorter2,
  7. A Algra1,
  8. for the LiLAC Study Group*
  1. 1Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
  2. 2Department of Rehabilitation, University Medical Centre Utrecht; Rehabilitation Centre De Hoogstraat, Utrecht
  3. 3Department of Neurology, Erasmus Medical Centre, Rotterdam, The Netherlands
  1. Correspondence to:
 A Algra
 Julius Centre, University Medical Centre Utrecht, Str 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands; a.algra{at}umcutrecht.nl
  • Received 26 January 2006
  • Accepted 4 May 2006
  • Revised 3 May 2006
  • Published Online First 30 May 2006

Abstract

Background: Stroke may have a major effect on survivors and on the healthcare system.

Aims: To study the functional status and use of healthcare facilities in long-term survivors of a transient ischaemic attack (TIA) or minor ischaemic stroke (MIS) and evaluate associations with baseline and follow-up characteristics.

Methods: Follow-up of patients who had participated in the Dutch TIA Trial or the European Atrial Fibrillation Trial was extended to a mean period of 15.6 years. Patients were interviewed through a postal questionnaire (n = 468) and a sample of this group was also interviewed at home (n = 198). Demographic data, information on comorbidity, functional status (Barthel Index, Frenchay Activities Index and modified Rankin Scale) and use of healthcare facilities were recorded.

Results: About one third of the survivors interviewed at home experienced any residual disability and 26% were moderately to severely handicapped. Factors associated with poor functional status were advanced age and the presence of any infarct on a baseline computed tomography scan, the recurrence of a new major stroke or the presence of comorbidity of locomotion. One third of survivors used any kind of professional care, which was predominantly related to the functional status at follow-up.

Conclusions: Recurrent stroke and the presence of comorbidity of locomotion are important determinants of long-term disability of survivors of a TIA or an MIS, which, in turn, is strongly associated with the long-term use of professional care. The need for measuring comorbidity with regard to functional status is recommended in research on stroke outcome.

Footnotes

  • Published Online First 30 May 2006

  • Funding: This study was funded by The Netherlands Heart Foundation (99.160) and the “Hersenstichting Nederland” (10F02.14).

  • Competing interests: None.

  • The investigators for the Dutch TIA Trial (neurologists of centres with ≥50 patients) are listed in the appendix in N Engl J Med1990;: . The investigators from the Dutch centres of the European Atrial Fibrillation Trial are listed in the appendix in Lancet1993;: .

  • Ethical approval: The ethics committee of the University Medical Centre Utrecht, The Netherlands, approved the protocol.

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