Article Text

PDF
Acute zonal occult outer retinopathy and multiple sclerosis
  1. R Q Hintzen1,
  2. L I van den Born2
  1. 1Department of Neurology, Erasmus MC, Rotterdam, The Netherlands
  2. 2The Rotterdam Eye Hospital, Rotterdam, The Netherlands
  1. Correspondence to:
 R Q Hintzen
 MS Centre, Department of Neurology, Erasmus University Medical School, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands; rhintzen{at}xs4all.nl

Abstract

The case of a 30-year-old woman who had two episodes of photopsia along with sudden-onset monocular visual field defects, developing into bilateral tunnel vision within 4 years, is reported. She also had episodes of a right hemiparesis and right-sided hypoaesthesia, accompanied by severe fatigue. This patient fulfilled the criteria for both clinically definite multiple sclerosis and acute zonal occult outer retinopathy (AZOOR). AZOOR can have an onset with monocular visual field loss, and can be distinguished from optic neuritis. In addition, some observations suggest common neuropathological and inflammatory mechanisms between multiple sclerosis and AZOOR.

  • AZOOR, acute zonal occult outer retinopathy
  • CSF, cerebrospinal fluid
  • MRI, magnetic resonance imaging

Statistics from Altmetric.com

Footnotes

  • Published Online First 25 July 2006

  • Funding: RQH is supported by the Dutch MS Research Foundation and by The Netherlands Organisation for Scientific Research (NWO).

  • Competing interests: None.

  • Consent was obtained for publication of the patient’s details described in this report.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.