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Spinal endoscopic biopsy in the diagnosis of central nervous system neurosarcoidosis
  1. T Fukushima1,
  2. M Shirota1,
  3. M Waragai1,
  4. T Yonemitsu2,
  5. T Yamaguchi3,
  6. K Yamada3,
  7. M Tannno4
  1. 1Division of Neurology, JR Tokyo General Hospital, Tokyo, Japan
  2. 2Department of Neurosurgery, JR Tokyo General Hospital, Tokyo, Japan
  3. 3Department of Respiratory Medicine, JR Tokyo General Hospital, Tokyo, Japan
  4. 4Department of Pathology, JR Tokyo General Hospital, Tokyo, Japan
  1. Correspondence to:
 Dr M Waragai
 Division of Neurology, JR Tokyo General Hospital, 2-1-3, Yoyogi, Shibuya-ku, Tokyo 151-8528, Japan; warawaram2002{at}aol.com

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A 55 year old woman was admitted to our hospital for progressive spastic paraparesis in March 2005. She had no history of systemic disease including sarcoidosis. Cerebrospinal fluid examination showed pleocytosis and increased protein levels. Gadolinium enhanced, T1 weighted, magnetic resonance imaging (MRI) performed at the time disclosed diffuse meningeal enhancement from the cerebral basal cistern including the pituitary stalk (fig 1A), brain stem to the spinal cord, and the nodular lesions …

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