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Misleading conclusions on rt-PA treatment in the very elderly
  1. P C A J Vroomen1,
  2. M Uyttenbogaart1,
  3. G J Luijckv1
  1. 1Department of Neurology, University Medical Centre Groningen, Groningen 9700 RB, Netherlands; c.a.j.vroomen@neuro.umcg.nl

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    The effectiveness of rt-PA in the elderly is an important but as yet incompletely resolved topic. In a recent paper in this journal,1 Mouradian et al provide convincing data that patients older than 80 years who receive rt-PA are less likely to have a favourable outcome than their younger counterparts. This is in keeping with our own data showing that 5 of 24 patients (21%) treated with rt-PA aged 80 years or older were independent (mRS 0–2) after three months, compared with 39 of 77 patients …

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