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J Neurol Neurosurg Psychiatry 2006;77:813 doi:10.1136/jnnp.2006.093468
  • Changes in insular infarcts
  • Editorial commentary

Cardiovascular and metabolic changes in insular infarcts: a delayed phenomenon?

  1. M Pasquini1,2,
  2. D Leys1
  1. 1Department of Neurology, Stroke Unit, Lille University Hospital, Lille, France
  2. 2Department of Neurology, University “La Sapienza”, Rome, Italy
  1. Correspondence to:
 M Pasquini
 Department of Neurology (EA2691), Lille University Hospital, F-59037 Lille, France; marta.pasquini{at}uniroma1.it

    Aggressive monitoring of electrocardiogram, blood pressure and blood glucose levels after 72 h in patients with insular infarcts is crucial in identifying whether they are prone to develop arrhythmias, hyperglycaemia and hypertension after the onset of stroke.

    Infarction of the insular cortex may be associated with autonomic sympathetic activation, leading to repolarisation changes and arrhythmias.1 Moreover, the involvement of the insular cortex in the infarct area has been reported to be associated with a higher frequency of hyperglycaemia, and this association does not depend on the volume of the lesion, or pre-existing diabetes mellitus.2 Patients with insular infarcts also show a marked increase in nocturnal blood pressure, and higher serum …

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