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J Neurol Neurosurg Psychiatry 2006;77:1090-1091 doi:10.1136/jnnp.2006.091728
  • Short report

Opsoclonus–myoclonus as a manifestation of Lyme disease

  1. L Peter1,
  2. J Jung1,
  3. C Tilikete2,
  4. P Ryvlin1,
  5. F Mauguiere1
  1. 1Service de Neurologie et d’épileptologie, Hôpital Neurologique, Lyon, France
  2. 2Service de Neuro-ophtalmologie, Hôpital Neurologique
  1. Correspondence to:
 L Peter
 Service de Neurologie et d’Epileptologie, Hôpital Neurologique, 59 Boulevard Pinel, 69003 Lyon, France;laure.peter{at}wanadoo.fr
  • Received 25 February 2006
  • Accepted 17 May 2006
  • Revised 15 May 2006

Abstract

Opsoclonus–myoclonus syndrome (OMS) is a rare condition that includes chaotic multidirectional saccadic eye movements associated with myoclonus and ataxia. In adults, it is usually considered to be an autoimmune disease occurring either in a paraneoplastic context or after central nervous system infection. We report the case of a patient who presented with the classic features of OMS as a manifestation of acute Borrelia burgdorferi infection that was shown both on serum and cerebrospinal fluid examination. The outcome was favourable after prolonged antibiotic treatment. Lyme disease could be added to the list of aetiologies to be screened in OMS, as it would allow effective treatment and avoidance of unnecessary investigations.

Footnotes

  • Competing interests: None declared.

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