Article Text

Download PDFPDF
Does chronic subthalamic nucleus stimulation in advanced Parkinson’s disease cause invalidating cognitive and behavioural dysfunctions?
  1. J D Speelman,
  2. H M M Smeding,
  3. B Schmand
  1. Academic Medical Center, Meibergdreef, Amsterdam, The Netherlands
  1. Correspondence to:
 J D Speelman
 Academic Medical Center, Postbus 22660, Meibergdreef 9, 1100 DD Amsterdam, The Netherlands;j.d.speelman{at}amc.uva.nl

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Cognitive and behavioural dysfunctions in patients with Parkinson’s disease

Chronic deep brain stimulation (DBS) of the subthalamic nucleus (STN) accomplishes favourable long-term improvements of motor symptoms in selected patients with advanced Parkinson’s disease.1 However, disagreement exists about the occurrence of cognitive and behavioural sequelae and their clinical significance. In a large cohort study with 3 years follow-up, Funkiewiez et al2 concluded that STN stimulation did not lead to global cognitive deteriorations. Rodriguez-Oroz et al,1 on the other hand, reported cognitive and behavioural dysfunction in 15 of 49 (30%) patients 3–4 years after surgery. In 11 patients, the dysfunctions were moderate to severe. However, they remarked that the severity of the adverse events did not …

View Full Text

Footnotes

  • Competing interests: None declared.

Linked Articles