Towards a common pathway for narcolepsy and rapid eye movement sleep behaviour disorder
- Correspondence to: Dr Rainer Dziewas Department of Neurology, University Hospital of Münster, Albert-Schweitzer-Strasse 33, 48129 Münster, Germany; dziewas{at}uni-muenster.de
- Received 4 October 2006
- Accepted 4 October 2006
- Revised 4 October 2006
Robust association between narcolepsy and RBD
Following the pioneering work of Schenk and Mahowald,1 a robust association of idiopathic narcolepsy and rapid eye movement (REM) sleep behaviour disorder (RBD) has recently been confirmed, suggesting that around one third of patients with narcolepsy have concomitant RBD.2 Although particularly severe cases with frequently occurring cataplexies and other associated symptoms of narcolepsy seem to be affected, the pathophysiological link between narcolepsy and RBD remains to be elucidated.
Contributing to this topic, in this issue, Mathis et al3(see p 427) report on a HLA DR2-negative patient who …
