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J Neurol Neurosurg Psychiatry 2007;78:662 doi:10.1136/jnnp.2006.109041
  • Acute ischaemic stroke
  • Editorial commentary

Thrombolysis therapy in octogenarians

  1. Valeria Caso,
  2. Maurizio Paciaroni,
  3. Giancarlo Agnelli
  1. Stroke Unit and Division of Internal and Cardiovascular Medicine, University of Perugia, Italy
  1. Correspondence to:
 Dr Valeria Caso
 Stroke Unit and Division of Internal and Cardiovascular Medicine, Ospedale Santa Maria della Misericordia, 06156 Perugia, Italy; vcaso{at}hotmail.com
  • Published Online First 21 February 2007

Octogenarians can be selected for thrombolysis therapy after CT scan without a detrimental effect on outcome

In the current issue of JNNP, Ringleb et al1 report data on patients, either younger or older than 80 years, treated with systemic thrombolysis for an acute ischaemic stroke (see page 690). Interestingly, the group of octogenarians were analysed with respect to the initial imaging modality (MRI or CT). The overall rate of haemorrhage and improved efficacy outcomes was not significantly different in the two age groups and no significant difference was observed for efficacy outcomes in MRI versus CT patients.

Ringleb et al1 deal …

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