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Devastating calcinosis in a patient with adult onset myositis
  1. L V Prasad Korlipara1,
  2. Patrick Kiely2,
  3. Istvan Bodi3,
  4. Fred Schon4
  1. 1Department of Neurology, St Georges Hospital, London, UK
  2. 2Department of Rheumatology, St Georges Hospital, London, UK
  3. 3Department of Neuropathology, Kings College Hospital, London, UK
  4. 4Department of Neurology, St Georges Hospital, London, UK
  1. Correspondence to:
 Dr Fred Schon
 Department of Neurology, St Georges Hospital, Blackshaw Road, London SW17 0QT, UK; Frederick.schon{at}mayday.nhs.uk

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A 62-year-old Indian woman presented initially in 1993 with swallowing difficulty, limb weakness, bilateral ptosis and Raynaud’s phenomenon. Investigation revealed an elevated creatine kinase and muscle biopsy suggested polymyositis. She responded well to treatment with prednisolone and azathioprine, which was gradually reduced and finally discontinued in 2004. She re-presented acutely unwell in 2006 with weight loss, dysphagia and gross weakness. Examination revealed cutaneous calcinotic plaques in both thighs and buttocks (fig 1), bilateral ptosis and global limb weakness. She was unable to stand erect, walking with a bent spine (fig 2A).

Figure 1

 Soft tissue …

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