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- Published on: 13 April 2016
- Published on: 13 April 2016
- Published on: 13 April 2016Migrainous scintillating scotoma and high-grade ICA stenosis: Why the link to CSD is plausibleShow More
Dear Editor
Leão discovered the spreading negative slow voltage variations in response to either direct current electrical stimulation or bilateral occlusion of the internal carotid artery in 1947. Both neurones and astrocytes depolarise during a spreading negative slow voltage variation, thereby inducing transmembraneous ionic shifts and intracellular oedema [1]. Under anoxia or severe ischaemia, this spreading...
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None declared. - Published on: 13 April 2016Migrainous scintillating scotoma and high-grade ICA stenosis: is the link to CSD plausible?Show More
Dear Editor
In a patient with high-grade internal carotid artery (ICA) stenosis and frequent migraine aura-like symptoms, Dreier et al [1] demonstrated widely scattered focal laminar cortical infarcts and resolution of visual symptoms following corrective surgery. These authors carry forward the speculation that brain ischemia-related cortical spreading depression (CSD) underlies the associated visual phenomena....
Conflict of Interest:
None declared.