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Transverse myelitis (TM), which is characterised by focal spinal-cord inflammation, may be idiopathic, parainfectious or disease associated. Diseases associated with TM include demyelinating conditions and connective tissue disorders. Apart from TM due to direct spinal-cord infection, TM is autoimmune.1 Acute motor axonal neuropathy (AMAN), a subtype of Guillain–Barre syndrome (GBS), is characterised by peripheral motor axonal neuropathy, is autoimmune and usually post-infectious.
To our knowledge, there are no adult reports of simultaneous TM and AMAN. We report a case of concomitant TM and AMAN in an adult and describe the response to immune modulation.
A 19-year-old male presented to the neurology services with a 2-day history of progressive bilateral lower limb weakness, urinary retention and a band of numbness around the waist extending into the feet. Two weeks previously, he had a diarrhoeal illness lasting 3 days.
Muscle strength testing revealed weakness of right hip flexion (MRC grade 4), bilateral knee flexion (grade 3), …