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Nerve biopsy without muscle sampling: is it enough for diagnosing vasculitis?
  1. Laurent Magy,
  2. Jean-Michel Vallat
  1. Service et Laboratoire de Neurologie, CHU Limoges, Limoges, France
  1. Dr Laurent Magy, Service et Laboratoire de Neurologie, CHU Limoges, 2 Avenue Martin Luther King, 87042 Limoges Cedex, France; magy{at}neuf.fr

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Vasculitides are a group of disorders that have in common the presence of inflammation of vessel walls, with or without necrosis. Peripheral neuropathy caused by vasculitis is often part of a multisystem disorder but vasculitis may be confined to peripheral nerves.1 Because vasculitides are potentially disabling but treatable disorders, histological demonstration of vasculitis has important implications. Bennett and colleagues2 describe their experience of the use of nerve and muscle biopsy in the diagnosis of vasculitis (see page 1376). This study provides exhaustive clinical and laboratory data on 53 cases of biopsy proven systemic and non-systemic vasculitic neuropathy. The authors show that in their hands, combined muscle and nerve …

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