rss
J Neurol Neurosurg Psychiatry 2008;79:594-597 doi:10.1136/jnnp.2007.125401
  • Short report

Combined EEG-fMRI and tractography to visualise propagation of epileptic activity

This article has been Unlocked
  1. K Hamandi1,
  2. H W R Powell1,
  3. H Laufs1,
  4. M R Symms1,
  5. G J Barker2,
  6. G J M Parker3,
  7. L Lemieux1,
  8. J S Duncan1
  1. 1
    Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, London, UK
  2. 2
    Institute of Psychiatry, Kings College London, London, UK
  3. 3
    Imaging Science & Biomedical Engineering, The University of Manchester, Manchester, UK
  1. Dr K Hamandi, The Epilepsy Unit, University Hospital of Wales, Cardiff CF14 4XW, UK; hamandik{at}cardiff.ac.uk
  • Received 25 May 2007
  • Revised 7 November 2007
  • Accepted 26 November 2007
  • Published Online First 20 December 2007

Abstract

In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modelling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.

Footnotes

  • Competing interests: None declared.

This article has been Unlocked

This Article

  1. Abstract
  2. Full text
  3. PDF
  4. All versions of this article:
    1. jnnp.2007.125401v1
    2. 79/5/594 most recent

Responses

  1. Submit a response
  2. No responses published

Register for free content

The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.

Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.

BMJ Careers - Latest neurology and neurosurgery jobs