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J Neurol Neurosurg Psychiatry 80:88-90 doi:10.1136/jnnp.2008.147793
  • Short report

Mobility and falls in people with Huntington’s disease

Table 1 Comparison of scores for all outcomes for the whole group and for the subgroups (non-fallers vs recurrent fallers)
Outcome Whole group Subgroup: non-faller Subgroup: recurrent faller
Mean (SD) age 56.6 (11.7), BMI 24.7(5.5); 16 males: eight females Mean (SD) age 55.2 (6.8), BMI 22.9 (4.3); six males: four females Mean (SD) age 57.6 (14.4), BMI 25.9 (6.1); 10 males: four females
Unified Huntington’s Disease Rating Scale motor score† 48 (28 to 80) 43 (28 to 72) 52 (36 to 68) (approximate 95% CI of difference −19.7 to 3.9)
Total functional capacity† 7 (3 to 11) 8 (4 to 11) 5.5 (3 to 9) (approximate 95% CI of difference −0.03 to 3.9)
Functional Assessment Scale† 18 (7 to 25) 21 (11 to 25) 14 (9 to 22)* (approximate 95% CI of difference 1.5 to 10.1)
Independence scale‡ 77.5 (50 to 95) 81.9 (10.7) 67. 5 (10.1)** (95% CI of difference 4.5 to 24.3)
Daily right step count‡ 4978 (2185) 6729 (1494) 3853 (1796)** (95% CI difference 1376 to 4373 steps)
Steps/minute sustained for 60 min‡ 24.4 (9.4) 30 (6.6) 20 (9)* (95% CI of difference 2 to 17 steps/min)
Gait speed (m/s)‡ 0.88 (0.24) 1.03 (0.2) 0.8 (0.2)* (95% CI of difference 0.05 to 0.45 m/s)
Activities-Specific Balance Confidence Scale-UK (%)‡ 60.7 (27.4) 77.5 (13.9) 47.9 (28.6)** (95% CI of difference 10.6 to 48.6%)
Berg Balance Scale† 41 (18 to 54) 45 (33 to 54) 38 (18 to 48)** (approximate 95% CI of difference 2.3 to 17.8)
“Timed Up & Go” test (s)† 14.2 (7.7 to 52.6) 12.6 (7.7 to 16.6) 15.6 (7.7 to 52.6)** (approximate 95% CI of difference 0.07 to 15.4 s)
  • Recurrent fallers and non-fallers were assessed for between-group differences.

  • **Significant difference between fallers and non-fallers at the 0.01 level (two-tailed).

  • *Significant difference at the 0.05 level (two-tailed).

  • †Median (range) data are presented.

  • ‡Mean (SD) data are presented.

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