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J Neurol Neurosurg Psychiatry 80:273-278 doi:10.1136/jnnp.2008.150185
  • Research paper

Disappearing hyperdense middle cerebral artery sign in ischaemic stroke patients treated with intravenous thrombolysis: clinical course and prognostic significance

Table 3 Functional outcome at 3 months against change in NIHSS at 2 h in HMCAS-D and HMCAS-P subgroups
Change in NIHSS score at 2 h after baseline Good functional outcome (mRS 0–2 at 3 months) (n (%)) (p = 0.01)
HMCAS-D HMCAS-P
<0 (i.e. worsening) 20 (27.4%) 12 (10.1%)
 = 0 (no change) 34 (19.9%) 29 (12.9%)
 = 1 (improvement) 23 (37.1%) 6 (7.1%)
     = 2 28 (40.6%) 15 (23.1%)
     = 3 27 (42.2%) 17 (40.5%)
     = 4 20 (43.5%) 5 (15.6%)
     = 5 11 (39.3%) 10 (50.0%)
    >5 115 (71.4%) 29 (49.2%)
  • HMCAS-D, hyperdense middle cerebral artery sign, disappearance; HMCAS-P, hyperdense middle cerebral artery sign, persistence; mRS, median Rankin Scale score; NIHSS, National Institute of Health Stroke Scale.

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