Table 1 Multivariable logistic regression model of factors associated with secondary progression
| Factor | Odds ratio (95% CI) | p Value |
| Parity | ||
| Nulliparous | (Reference) | 0.81 |
| Parous | 0.93 (0.50 to 1.72) | |
| Age at disease onset* | 0.98 (0.95 to 1.01) | 0.27 |
| Disease duration* | 1.05 (1.03 to 1.09) | <0.0005 |
| Immunomodulatory treatment use† | ||
| No | (Reference) | 0.005 |
| Yes | 0.23 (0.08 to 0.65) | |
| Symptom at onset | ||
| Motor | (Reference) | 0.52 |
| Sensory | 1.00 (0.43 to 2.37) | |
| Brainstem/cerebellar | 1.34 (0.46 to 3.84) | |
| Visual | 1.67 (0.71 to 3.94) | |
| Other | 1.05 (0.24 to 4.67) |
-
Hosmer and Lemeshow p = 0.13.
-
*Per year increase.
-
†For at least 1 year before secondary progression or censoring.
