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MRI development of early white matter signs in cerebellar-type multisystem atrophy
  1. B M de Jong
  1. Dr B M de Jong, Department of Neurology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30 001, 9700 RB Groningen, The Netherlands; b.m.de.jong{at}neuro.umcg.nl

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About 8 months after the gradual onset of subtle gait ataxia, unstable bicycle riding and slurring of speech under stressful circumstances, a woman in her mid 40s underwent MRI which was assessed as normal (fig 1A). She was referred for a second opinion to our hospital with mild gait ataxia, slight interruptions in the fluency of high speed articulation and small saccades during ocular pursuit. Follow-up MRI was normal (fig 1B) although in retrospect a slight signal increase in the left …

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