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Research paper
Comparative epidemiology of stroke and acute myocardial infarction: the Dijon Vascular project (Diva)
  1. A Gentil1,
  2. Y Béjot1,
  3. L Lorgis2,
  4. J Durier1,
  5. M Zeller2,
  6. G-V Osseby1,
  7. G Dentan3,
  8. J-C Beer2,
  9. T Moreau1,
  10. M Giroud1,
  11. Y Cottin2
  1. 1
    The Dijon Stroke Registry (EA 4184), University of Burgundy, University Hospital and Faculty of Medicine of Dijon, Dijon, France
  2. 2
    The Observatoire des Infarctus de Côte-d’Or (RICO), LPPCE, IFR Santé-STIC, University of Burgundy, University of Hospital and Faculty of Medicine of Dijon, Dijon, France
  3. 3
    The Cardiology Department, Clinique de Fontaine, Dijon, France
  1. Correspondence to Dr Y Bejot, Department of Neurology, University Hospital, 3 Rue du Faubourg Raines, 21000 Dijon, France; ybejot{at}yahoo.fr

Abstract

Background: Despite a common pathophysiological mechanism (ie, atherosclerosis) and similar vascular risk factors, few reliable studies have compared the epidemiology of stroke and acute myocardial infarction (AMI).

Methods: All first ever cases of stroke and AMI in Dijon, France (151 846 inhabitants) from 2001 to 2006 were prospectively recorded. The 30 day case fatality rates (CFRs) and vascular risk factors were assessed in both groups.

Results: Over the 6 years, 1660 events (1020 strokes and 640 AMI) were recorded. Crude incidence of stroke was higher than that of AMI (112 vs 70.2/100 000/year; p<0.001). With regard to sex, the relative incidence of stroke compared with AMI was 0.88 (95% CI 0.60 to 1.29; p = 0.51) in women <65 years and 2.32 (95% CI 1.95 to 2.75; p<0.001) in those >65 years whereas it was 0.60 (95% CI 0.42 to 0.86; p<0.001) in men below 55 years, 1.01 (0.81 to 1.24, p = 0.96) in those between 55 and 75 years and 2.01 (95% CI 1.48 to 2.71; p<0.001) at 75 years and older. CFRs at 30 days were similar for stroke and AMI (9.80% vs 9.84%; p = 0.5). Hyperglycaemia (>7.8 mmol/l) at onset was significantly associated with higher CFR in both stroke and AMI patients. The prevalence of male sex, hypercholesterolaemia and diabetes was higher in AMI patients whereas hypertension was more frequent in stroke patients.

Conclusion: These findings will help health care authorities to evaluate future needs for stroke and AMI services, and to develop secondary prevention strategies.

https://doi.org/10.1136/jnnp.2009.172551

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    Footnotes

    • Funding This work was supported by a grant from the University Hospital of Dijon and the Regional Council of Burgundy in 2006. The sponsors of the study had no role in the project, in data collection, data interpretation and analysis, or in writing the publication.

    • Competing interests None.

    • Ethics approval The Diva project was approved by the ethics committee of the University Hospital of Dijon.