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Mortality after traumatic spinal cord injury: 50 years of follow-up
  1. Ellen Merete Hagen1,2,
  2. Stein Atle Lie3,
  3. Tiina Rekand1,
  4. Nils Erik Gilhus1,2,
  5. Marit Gronning1,2
  1. 1Department of Neurology, Haukeland University Hospital, Bergen, Norway
  2. 2Section of Neurology, Department of Clinical Medicine, University of Bergen, Bergen, Norway
  3. 3Unifob Health, University Research Bergen, Department of Health, Bergen, Norway
  1. Correspondence to Dr E M Hagen, Department of Neurology, Haukeland University Hospital, Jonas Lies vei 65, N-5021 Bergen, Norway; ellen.merete.hagen{at}helse-bergen.no

Abstract

Objective To study mortality and causes of death in an unselected geographically defined cohort of patients with traumatic spinal cord injury (TSCI), 1952–2001.

Methods Patients were identified from hospital records. The date of death was obtained from the National Population Register, and causes of death recorded by linkage to the Norwegian Cause of Death Registry. Patient mortality was compared with mortality in the Norwegian population using standardised mortality ratios (SMR) adjusted for age and gender.

Results 401 patients (70 women and 331 men) were identified. By 31 August 2008, 173 were dead. Median survival time in deceased patients was 7.4 years; 6.9 years for patients with cervical injuries and 8.2 years for patients with thoracolumbosacral injuries (TLS). TSCI patients had an increased mortality (SMR 1.85) compared with the Norwegian population. SMR did not change during the observation period. SMR was significantly higher for women than for men (2.88 vs 1.72), and higher in patients with complete TSCI compared with patients with incomplete TSCI (4.23 vs 1.25). SMR was 6.70 for patients with complete cervical injuries and 3.07 for patients with complete TLS injuries. Cause specific SMR were 1.96 for respiratory disease, and for suicide including accidental poisoning 3.70 for men and 37.59 for women.

Conclusions Patients with a TSCI, and especially women, have an increased mortality despite modern treatment and care. Special attention should be paid to respiratory dysfunction and pulmonary infections, and to prevent suicide and accidental poisoning.

  • Epidemiology
  • Neuroepidemiology

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Footnotes

  • Competing interests None.

  • Ethics approval The study was approved by the Regional Committee for Medical Research Ethics, the Norwegian Data Inspectorate and the Directorate for Health and Social Affairs.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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