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Lonergan et al studied the prevalence of multiple sclerosis (MS) in three regions of Ireland (see page 317) and attempted, in a case control manner, to compare winter vitamin D levels and HLA-DRB1:1501 status to try to understand the drivers of MS prevalence geoepidemiology in Ireland.1
For many years it has been recognised that MS prevalence varies significantly around the world, with prevalence of MS being highest in those of northwest European ancestry and increasing with latitude.2 3 A latitudinal gradient of MS prevalence provides the impetus for generation of a priori …
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