We read an interesting review and meta-analysis of published articles pertaining to cerebral amyloid angiopathy (CAA) by Samarasekera and collegues published in March 2012 issue of our esteemed journal1. The effforts made by the authors are worth appreciation. The previously considered to be a rare neurological curosity, CAA is now recognised as an important cause of spontaneous intracerebral haemorrhage and cognitive impairment in the elderly but still under-recognised2. Further prospective studies in this direction are mendatory to strengthen the diagnostc criteria with the help of modern neuroimaging and biopsy of brain and leptomeninges as and when possible. New treatment and management options described in earlier issue of this article in form of reduction of blood pressure, statins, anti-inflammatory, immunomodulators and surgery requires further trials in this direction2,3. Results of surgery are not as dismal as it was thout to be previously as described earlier2 and our own observation3. REFFRENCES- 1-Samarasekara N, Smith C, Salman R Ai-Shahi. The asssociation between cerebral amyloid angiopathy; systematic review and meta-analysis. J. Neurol Neurosurg Psychiatry 2012; 83: 275-281. 2-Andreas Charidimou, Qiang Gang, David J Werring. Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum. J Neurol Neurosurg Psychiatry.2012;83:124-137. 3-Khichar Shubhakaran. Personal onservation.

Conflict of Interest:

None declared