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Abstracts from the Association of British Neurologists Annual Meeting 2011
095 A cupric pregnancy: thirteenth time lucky
  1. T Young,
  2. G Downey,
  3. M B Maheshwari,
  4. D J Nicholl
  1. University Hospital Birmingham, UK

Abstract

Recurrent miscarriage is a less recognised feature of Wilson Disease (WD) and adequate treatment can alter the outcome of pregnancies favourably. WD is a recessively inherited disorder of copper metabolism due to mutations in the ATP7B gene, which encodes for a copper-transporting P-type ATPase. Recurrent miscarriage is a complication of untreated WD. It has been reported that miscarriages can predate neurological symptoms, and treatment with copper chelation improves the rate of successful pregnancies. We describe a patient with a background of unexplained recurrent miscarriages who was diagnosed with WD and subsequently gave birth to two children after treatment was commenced.

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Footnotes

  • Email: terence.young{at}uhb.nhs.uk

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