J Neurol Neurosurg Psychiatry 83:469-470 doi:10.1136/jnnp-2011-300311
  • PostScript
  • Letter

Myasthenia gravis can cause camptocormia

  1. Satoshi Ueno
  1. Department of Neurology, Nara Medical University, Kashihara, Nara, Japan
  1. Correspondence to Dr Kataoka, Department of Neurology, Nara Medical University 840 Shijo-cho, Kashihara, Nara 634-8522, Japan; hk55{at}
  1. Contributors HK was responsible for the overall study design and wrote the manuscript. HK and TK contributed to the analysis and interpretation of data. HK and SU contributed to drafting and critical revision of a part of the submitted materials.

  • Received 15 April 2011
  • Revised 31 August 2011
  • Accepted 2 September 2011
  • Published Online First 20 September 2011


Camptocormia is characterised by an abnormal posture of the trunk with marked flexion of the thoracolumbar spine. The spinal curvature resolves when the affected individual lies in the supine position. Camptocormia can be associated with metabolic, spinal, neuromuscular, psychiatric, neurogenic and movement disorders.1 We describe an unusual patient with myasthenia gravis (MG) who had camptocormia that responded to edrophonium.

Case report

In February 2009, a 75-year-old woman with a history of hypertension and angina noticed lower extremity weakness, numbness below the trunk and forward flexion of the lumbar spine. In April, she underwent surgery to treat ossified thoracic yellow ligaments, and the numbness resolved. However, weakness and forward flexion of the lumbar spine gradually worsened, and in August she required a cane to walk. In October, she presented with dropped head. The severity of forward …

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