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Apathy and impaired recognition of emotion: are they related in Parkinson’s disease?
  1. Kathy Dujardin1,2,
  2. Renaud Lopes1,3
  1. 1Degenerative and Vascular Cognitive Disorders Research Unit, University of Lille 2, Lille, France
  2. 2Department of Neurology and Movement Disorders, Lille University Medical Center, Lille, France
  3. 3Lille In Vivo Imaging Core Facility, Institut de Médecine Prédictive et de Recherche Thérapeutique, Lille University Medical Center, Lille, France
  1. Correspondence to Professor Kathy Dujardin, Neurologie et Pathologie du Mouvement, Neurologie A, Hôpital Salengro, Centre Hospitalier Universitaire, Lille cedex F-59037, France; kathy.dujardin{at}univ-lille2.fr

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Apathy is one of the most disabling behavioural disorders in Parkinson's disease (PD). It corresponds to a set of behavioural, emotional and cognitive features, such as reduced interest and participation in the main activities of daily living, a lack of initiative, a trend towards early withdrawal from initiated activities, indifference and flattening of affect. Its prevalence in PD ranges from 17% to 70%.1 This broad variability is related to heterogeneous population characteristics (the general population, patients in specialist departments, institutionalised patients, etc), different assessment procedures (clinical assessments, scores on non-specific or specific scales, etc) and the overlap between the clinical manifestations of apathy and those of other disorders (such as depression, anhedonia, cognitive decline and even some personality traits). The mechanisms that …

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