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Deep brain stimulation surgery under general anaesthesia with microelectrode recording: the best of both worlds or a little bit of everything?
  1. Peter C Warnke
  1. Correspondence to Professor Peter C Warnke, Department of Neurosurgery, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA; pwarnke{at}surgery.bsd.uchicago.edu

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The factions of functional neurosurgeons performing deep brain stimulation (DBS) for movement disorders are fairly well separated. The physiology aficionados subscribe to the doctrine that only meticulous microelectrode recording (MER) in the awake patient without any sedative interference gives optimal results. The believers in the accuracy of imaging claim that targeting the subthalamic nucleus (STN) the globus pallidum internus can be achieved precisely from MRI or MR/CT fusion alone with equally good outcomes as measured on the Unified Parkinson's Disease Rating Scale (UPDRS) and the ability to postoperatively cut the Levodopa (L-DOPA) equivalent amount of medication.

Fluchere and colleagues seem to have found a Salomonic compromise that could satisfy both camps.1 In an impressively large cohort of 126 patients they used ‘controlled …

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