Footnotes

• Contributors JS contributed this study by design and conceptualisation, analysis of data and drafting the manuscript. NK contributed this study by acquisition of data and drafting the manuscript. ES contributed this study by acquisition of data and drafting the manuscript. MI contributed this study by acquisition of data and drafting the manuscript. RN contributed this study by analysis of data and drafting the manuscript. HK contributed this study by analysis of data and drafting the manuscript. YI contributed this study by conceptualisation, analysis of data and drafting the manuscript. MY contributed this study by analysis of data and revising the manuscript. TT contributed this study by acquisition of data, analysis of data and drafting the manuscript. SC contributed this study by acquisition of data, analysis of data and drafting the manuscript. MK contributed this study by conceptualisation and revising the manuscript. FT contributed this study by conceptualisation and revising the manuscript. GS contributed this study by design and conceptualisation and revising the manuscript. All the above-mentioned members approved the final version of this paper to be published.

• Funding This study was sponsored by a global COE grant from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and a grant from the Ministry of Health, Welfare and Labor of Japan.

• Competing interests None.

• Patient consent Obtained.

• Ethics approval The study was approved by the Institutional Review Board of the Nagoya University School of Medicine.

• Provenance and peer review Not commissioned; externally peer reviewed.