E05 6-,9- And 15-Month Change in Cortical Thickness and Region-Of-Interest Volume And Diffusion Metrics in Huntington’s Disease: Informing Trial Design

NZ Hobbs; RE Farmer; EM Rees; JH Cole; S Haider; IB Malone; R Sprengelmeyer; H Johnson; HP Müeller; SD Sussmuth; RAC Roos; A Durr; C Frost; RI Scahill; GB Landwehrmeyer; SJ Tabrizi

doi:10.1136/jnnp-2014-309032.108

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E05 6-,9- And 15-Month Change in Cortical Thickness and Region-Of-Interest Volume And Diffusion Metrics in Huntington’s Disease: Informing Trial Design

Authors

NZ Hobbs 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
RE Farmer 2Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK PubMed articles Google scholar articles
EM Rees 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
JH Cole 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
S Haider 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
IB Malone 3Dementia Research Centre,UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
R Sprengelmeyer 4Department of Neurology, Ulm University, Ulm, Germany PubMed articles Google scholar articles
H Johnson 5Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA PubMed articles Google scholar articles
HP Müeller 4Department of Neurology, Ulm University, Ulm, Germany PubMed articles Google scholar articles
SD Sussmuth 4Department of Neurology, Ulm University, Ulm, Germany PubMed articles Google scholar articles
RAC Roos 7ICM (Brain and Spine Institute), APHP- Department of Genetics and INSERM UMR S679, Salpêtrière University Hospital, Paris, France PubMed articles Google scholar articles
A Durr 6Department of Neurology,Leiden University Medical Centre, Leiden, Netherlands PubMed articles Google scholar articles
C Frost 2Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK PubMed articles Google scholar articles
RI Scahill 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles
GB Landwehrmeyer 4Department of Neurology, Ulm University, Ulm, Germany PubMed articles Google scholar articles
SJ Tabrizi 1Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK PubMed articles Google scholar articles

Citation

Hobbs N, Farmer R, Rees E, et al

E05 6-,9- And 15-Month Change in Cortical Thickness and Region-Of-Interest Volume And Diffusion Metrics in Huntington’s Disease: Informing Trial Design

Journal of Neurology, Neurosurgery & Psychiatry 2014;85:A37.

Publication history

First published September 17, 2014.

Online issue publication

April 13, 2016

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