A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN

Hazuki Watanabe; Naoki Atsuta; Akihiro Hirakawa; Ryoichi Nakamura; Masahiro Nakatochi; Shinsuke Ishigaki; Aritoshi Iida; Shiro Ikegawa; Michiaki Kubo; Daichi Yokoi; Hirohisa Watanabe; Mizuki Ito; Masahisa Katsuno; Yuishin Izumi; Mitsuya Morita; Kazuaki Kanai; Akira Taniguchi; Ikuko Aiba; Koji Abe; Koichi Mizoguchi; Masaya Oda; Osamu Kano; Koichi Okamoto; Satoshi Kuwabara; Kazuko Hasegawa; Takashi Imai; Akihiro Kawata; Masashi Aoki; Shoji Tsuji; Kenji Nakashima; Ryuji Kaji; Gen Sobue

doi:10.1136/jnnp-2015-311541

Article info

Neurogenetics

Research paper

A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN

Authors

Hazuki Watanabe Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Naoki Atsuta Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Akihiro Hirakawa Biostatistics and Bioinformatics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan PubMed articles Google scholar articles
Ryoichi Nakamura Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Masahiro Nakatochi Biostatistics and Bioinformatics Section, Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan PubMed articles Google scholar articles
Shinsuke Ishigaki Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Aritoshi Iida Laboratory for Bone and Joint Diseases, Center for Integrative Medical Science, RIKEN, Tokyo, Japan PubMed articles Google scholar articles
Shiro Ikegawa Laboratory for Bone and Joint Diseases, Center for Integrative Medical Science, RIKEN, Tokyo, Japan PubMed articles Google scholar articles
Michiaki Kubo Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan PubMed articles Google scholar articles
Daichi Yokoi Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Hirohisa Watanabe Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Mizuki Ito Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Masahisa Katsuno Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles
Yuishin Izumi Department of Clinical Neuroscience, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan PubMed articles Google scholar articles
Mitsuya Morita Division of Neurology, Department of Internal Medicine, Jichi Medical University, Tochigi, Japan PubMed articles Google scholar articles
Kazuaki Kanai Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan PubMed articles Google scholar articles
Akira Taniguchi Department of Neurology, Mie University Graduate School of Medicine, Tsu, Japan PubMed articles Google scholar articles
Ikuko Aiba Department of Neurology, National Hospital Organization, Higashinagoya National Hospital, Nagoya, Japan PubMed articles Google scholar articles
Koji Abe Department of Neurology, Okayama University Graduate School of Medicine, Okayama, Japan PubMed articles Google scholar articles
Koichi Mizoguchi Department of Neurology, National Hospital Organization, Shizuoka-Fuji National Hospital, Fujinomiya, Japan PubMed articles Google scholar articles
Masaya Oda Department of Neurology, Vihara Hananosato Hospital, Miyoshi, Japan PubMed articles Google scholar articles
Osamu Kano Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan PubMed articles Google scholar articles
Koichi Okamoto Department of Neurology, Geriatrics Research Institute, Maebashi, Japan PubMed articles Google scholar articles
Satoshi Kuwabara Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan PubMed articles Google scholar articles
Kazuko Hasegawa Division of Neurology, National Hospital Organization, Sagamihara National Hospital, Sagamihara, Japan PubMed articles Google scholar articles
Takashi Imai Division of Neurology, National Hospital Organization, Miyagi National Hospital, Miyagi, Japan PubMed articles Google scholar articles
Akihiro Kawata Department of Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan PubMed articles Google scholar articles
Masashi Aoki Department of Neurology, Tohoku University School of Medicine, Sendai, Japan PubMed articles Google scholar articles
Shoji Tsuji Department of Neurology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articles Google scholar articles
Kenji Nakashima Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan PubMed articles Google scholar articles
Ryuji Kaji Department of Clinical Neuroscience, Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, Japan PubMed articles Google scholar articles
Gen Sobue Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan PubMed articles Google scholar articles

Correspondence to Professor Gen Sobue, Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550 Japan; sobueg{at}med.nagoya-u.ac.jp

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Citation

Watanabe H, Atsuta N, Hirakawa A, et al

A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression of TTN

Journal of Neurology, Neurosurgery & Psychiatry 2016;87:851-858.

Publication history

Received June 16, 2015
Revised October 23, 2015
Accepted November 18, 2015
First published January 8, 2016.

Online issue publication

December 15, 2016

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