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Seasonality of tweets related to multiple sclerosis
  1. Alex Simpson,
  2. Marta Pereira,
  3. Selin Cooper,
  4. Sreeram V Ramagopalan
  1. Real World Evidence, Evidera, London, UK
  1. Correspondence to Dr Sreeram V Ramagopalan, Real World Evidence, Evidera, Metro Building, 6th Floor, 1 Butterwick, W6 8DL, London, UK; Sreeram.Ramagopalan{at}

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We read with interest the study by Moccia et al1 showing seasonality of searches for multiple sclerosis (MS) using Google, reflecting trends reported for disease relapses.2 The analysis of social media (eg, Twitter and Facebook) is an additional tool that is being used increasingly to answer research questions about disease spatiotemporal epidemiology.3 Patients are more and more using web technologies such as social media, blogs and forums to generate real-world evidence of potentially medically important issues. This content therefore serves as an important source of data about disease burden. Given the study by Moccia et al, we therefore sought to investigate whether or not there is seasonality to tweets regarding MS, as this may better reflect the ‘patient voice’.

Tweets from 2010–2015 that contained the words ‘MS relapse’ …

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