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In this special edition of Journal of Neurology, Neurosurgery, and Psychiatry, we highlight recent advances in stroke management. In 2015, a series of transformative neurointerventional trials established the benefit of mechanical thrombectomy in large vessel occlusion, dramatically changing the management of acute stroke and altering the natural history of this devastating stroke subtype. This breakthrough in science has forced a redesign of stroke care and reinvigorated research in the prevention and management of one of the leading causes of death and disability around the globe.
One of the most dramatic changes to emerge during the last few years has been the acceleration …