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Human immunodeficiency virus associated intracranial aneurysms: Report of three adult patients with an overview of the literature
  1. Kirti Ranchod
  1. Division of Neurology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa
    1. Mala Modi
    1. Division of Radiology, Department of Radiation Sciences, University of the Witwatersrand, South Africa
      1. Vinod Goolab
      1. Division of Neurosurgery, Department of Neurosciences, University of the Witwatersrand, South Africa
        1. Andre Mochan
        1. Division of Neurology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa
          1. Girish Modi (gmodicns{at}mweb.co.za)
          1. Division of Neurology, Department of Neurosciences, University of the Witwatersrand, Johannesburg, South Africa

            Abstract

            Background and purpose: Aneurysms have been described in HIV infected patients. These involve predominantly extracranial blood vessels with specific histological and clinical features. Intracranial aneurysms are rare and have been identified mainly in children.

            Methods: Case reports and literature review.

            Results: Three black South African HIV positive adult patients with intracranial aneurysms were identified. The clinical, laboratory and radiological features are described.

            Conclusions: Intracranial aneurysms occur in both adults and children infected with HIV. More information is required on this association. The frequency in terms of numbers of cases indicates that it is an uncommon association or manifestation of HIV. The characteristics of the aneurysms suggest that they are distinctive and not a chance or coincidental co-occurrence of congenital or arteriosclerotic aneurysms.

            • HIV
            • intracranial, aneurysm

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