Article Text

other Versions

PDF
Anti-MAG/SGPG associated neuropathy does not commonly cause distal nerve temporal dispersion
  1. F AA Gondim (gondimfranc{at}yahoo.com)
  1. Universidade Federal do Ceará, Brazil
    1. E A De Sousa (eadonias{at}hotmail.com)
    1. Cornell University, United States
      1. N Latov (nol2002{at}med.cornell.edu)
      1. Cornell University, United States
        1. H W Sander (hsander{at}svcmcny.org)
        1. Cornell University, United States
          1. R L. Chin (ruc9002{at}med.cornell.edu)
          1. Cornell University, United States
            1. T H Brannagan III (thb2006{at}med.cornell.edu)
            1. Cornell University, United States

              Abstract

              Patients with anti-MAG neuropathy have uniform slowing without temporal dispersion, but do usually have disproportionately distal slowing. We evaluated distal compound muscle action potential (CMAP) dispersion in 29 patients with anti-MAG/SGPG neuropathy (titers >=12800). Among 138 motor responses, 15% (tibial), 7.3% (peroneal), 10.7% (median) and 13.8% (ulnar) had distal CMAP duration > 9 ms. Disproportionate distal slowing with normal distal CMAP duration in the arms may be useful to differentiate CIDP from anti-MAG/SGPG associated neuropathy.

              • demyelination
              • myelin-associated glycoprotein
              • peripheral neuropathy
              • temporal dispersion

              Statistics from Altmetric.com

              Request permissions

              If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.