Autonomic dysfunction is common in Parkinson`s disease (PD).Amongst others, levodopa alteres cardiovascular reflexes.Deep brain stimulation of the subthalamic nucleus (STN-DBS) is an effective treatment for motor disability in patients with long-lasting PD. Since the basal ganglia are connected to areas involved in regulation of the autonomic nervous system (ANS)STN-DBS might affect ANS functions. This study aimed to investigate the influence of STN-DBS on ANS compared to effects of levodopa administration.
- Parkinson`s disease
- autonomic nervous system
- blood pressure
- subthalamic nucleus stimulation