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Acute necrotizing encephalopathy: a relapsing case in a european adult
  1. Alfonso Fasano (alfonso.fasano{at}rm.unicatt.it)
  1. Università Cattolica del Sacro Cuore Roma, Italy
    1. Gabriella Ferlazzo Natoli
    1. Università Cattolica del Sacro Cuore Roma, Italy
      1. Alessandro Cianfoni
      1. Università Cattolica del Sacro Cuore Roma, Italy
        1. Diana Ferraro
        1. Università Cattolica del Sacro Cuore Roma, Italy
          1. Giovanna Loria
          1. Università Cattolica del Sacro Cuore Roma, Italy
            1. Anna Rita Bentivoglio
            1. Università Cattolica del Sacro Cuore Roma, Italy
              1. Serenella Servidei
              1. Università Cattolica del Sacro Cuore Roma, Italy

                Abstract

                Acute necrotizing encephalopathy (ANE) is a rare disease, characterized by the rapid development of multiple, symmetrical brain lesions, affecting the thalamus bilaterally, the brainstem tegmentum and the cerebellar medulla. The clinical picture consists of a rapidly deteriorating encephalopathy which develops 1 to 3 days after a prodromal febrile illness. ANE has been related to influenza A virus infection, but to date it has also been associated with other viruses and mycoplasma. We report a case of ANE, characterized by a combination of unusual features.

                • acute necrotizing encephalopathy
                • coma
                • coxsackie
                • influenza A
                • virus

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