CADASIL (OMIM 125310) is an increasingly recognized adult-onset autosomal dominant vascular disease characterized by recurrent transient ischemic attacks (TIAs) and strokes (43% of patients), vascular dementia (6%), migraine with aura (40% of patients) and psychiatric disturbances (9% of patients); epilepsy has been reported in 2 to 10% of subjects.1 All patients revealed prominent signal abnormalities on brain MRI—leukoencephalopathy on T2- and small subcortical infarcts on T1-weighted images.2
- NOTCH3 gene
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.