Article Text

other Versions

Combined EEG-fMRI and tractography to visualise propagation of epileptic activity.
  1. Khalid Hamandi (hamandik{at}
  1. University Hospital of Wales, United Kingdom
    1. H.W.Robert Powell (robpowell{at}
    1. Institute of Neurology, United Kingdom
      1. Helmut Laufs (helmut{at}
      1. Johann Wolfgang Goethe-University Frankfurt am Main, Germany
        1. Mark R Symms (m.symms{at}
        1. Department of Clinical and Experimental Epilepsy, United Kingdom
          1. Gareth J Barker (g.barker{at}
          1. Institute of Psychiatry, United Kingdom
            1. Geoff JM Parker (geoff.parker{at}
            1. Imaging Science & Biomedical Engineering, United Kingdom
              1. Louis Lemieux (l.lemieux{at}
              1. Institute of Neurology, United Kingdom
                1. J S Duncan (j.duncan{at}
                1. Natl Hosp for Neurology & Neurosurgery, United Kingdom


                  In a patient with refractory temporal lobe epilepsy, EEG-fMRI showed activation in association with left anterior temporal interictal discharges, in the left temporal, parietal and occipital lobes. Dynamic causal modeling suggested propagation of neural activity from the temporal focus to the area of occipital activation. Tractography showed connections from the site of temporal lobe activation to the site of occipital activation. This demonstrates the principle of combining EEG-fMRI and tractography to delineate the pathways of propagation of epileptic activity.

                  • Dynamic Causal Modelling
                  • EEG-fMRI
                  • Temporal Lobe Epilepsy
                  • Tractography

                  Statistics from

                  Request permissions

                  If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.