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Camptocormia in Parkinson’s disease: an epidemiological and clinical study
  1. Dorina Tiple (dorinuca{at}
  1. University of Rome, Italy
    1. Giovanni Fabbrini (giovanni.fabbrini{at}
    1. University of Rome, Italy
      1. Carlo Colosimo (carlo.colosimo{at}
      1. University of Rome, Italy
        1. Donatella Ottaviani (donatellaottaviani{at}
        1. University of Rome, Italy
          1. Filippo Camerota (f.camerota{at}
          1. University of Rome, Italy
            1. Giovanni Defazio (gdefazio{at}
            1. University of Bari,Italy Department of Neurological and Psychiatric Neurosciences, Italy
              1. Alfredo Berardelli (alfredo.berardelli{at}
              1. University of Rome, Italy


                Background: Camptocormia is an abnormal flexion of the thoracolumbar spine during standing and walking that abates in the recumbent position.

                Methods: In a single-centre epidemiological and clinical study we investigated the prevalence of camptocormia in Parkinson’s disease (PD), and its relationship with the clinical features of PD. A total of 275 consecutive out-patients were systematically screened for camptocormia with a clinical evaluation. Patients who screened positive for camptocormia were subsequently reassessed by formal goniometric analysis. The demographic and clinical features of the patients with and without camptocormia were then compared.

                Results: we found a 6.9% (19/275, 95% confidence interval, 4.2 to 10.6) prevalence of camptocormia. Camptocormia was found in patients with more severe PD, as clinically assessed by the Hoehn and Yahr (HY) staging and the motor Unified Parkinson’s disease Rating Scale (UPDRS) part III, longer L-dopa treatment duration and greater L-dopa daily dose and presence of DSM-IV dementia. Camptocormia was reported to develop after the clinical onset of PD. No correlation was found between the degree of trunk flexion and age, duration of PD, UPDRS motor score, HY staging, and L-dopa treatment duration and dose. As a risk factor, the study identified previous vertebral surgery.

                Conclusions: Camptocormia, a relatively common sign in PD seems to be related to the clinical severity of PD.

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